Pure Saccharomyces Boulardii
Pure Saccharomyces Boulardii
60 Capsules Unflavored Capsules
Most probiotics struggle to make it through stomach acid and get to where they are needed in the GI tract. Even fewer can resist antibiotics. Our Pure S. Boulardii CNCM I-3799 strain, backed by Lesaffre's 170 years of expertise, resists both stomach acid & antibiotics to deliver microbiome protection where other probiotics fail.† This shelf-stable, hypoallergenic formula is extensively 3rd party tested in the USA, making it the gold standard.
Complete Transparency,
No Hidden Surprises
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Gluten, dairy & soy free
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No proprietary blends
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No unnecessary fillers
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Third-party lab tested
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Vegan & non-GMO
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Clinically studied strain
Supplement Facts & Ingredients
Supplement Facts & Ingredients

Other Ingredients: Vegetarian capsule (cellulose, water) and L-leucine.
^Minimum Colony-Forming Units at time of manufacture.
Third Party Tested
Third Party Tested
We partner exclusively with ISO 17025 accredited laboratories here in the USA to test for common allergens, heavy metals and microbiological contaminants. View certificate of analysis below.
How To Enjoy
How To Enjoy
Take 1 capsule daily, with or between meals, or as directed by a healthcare professional.
Capsules can be opened and mixed into food or beverage if required. Consume immediately after mixing.










Trusted by 1000s for better gut health

What Makes Us Different
Most supplement companies cut corners where you can't see - using overseas manufacturing, skipping independent testing and loading products with gut-irritating fillers. We take the harder, more expensive path because your gut health deserves better than “industry-standard”.


Third-Party Tested In The USA
Most companies only test their products internally - we do both. Our formulas get tested in-house, then verified again by independent ISO-certified labs where scientists screen for contaminants and validate our allergen-free promises. Because we believe your gut health journey deserves nothing less than exceptional quality.


Verified Customer Reviews

60-Day Money Back Guarantee
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every bottle.
Try any Essential Stacks product completely risk-free for 60 days. Not satisfied? Get a full refund - even if the bottle is empty. No questions asked, no explanations needed.

Frequently Asked Questions
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What does Saccharomyces Boulardii do for my gut health?
S. Boulardii is a beneficial probiotic yeast that supports your microbiome balance and digestive health. Unlike bacterial probiotics, it's naturally resistant to stomach acid and antibiotics, so it reaches your intestines alive and active.†
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How is this different from regular probiotics?
Most probiotics are bacteria based and may get destroyed by stomach acid or antibiotics. S. Boulardii is a hardy yeast that survives both, delivering 5 billion CFUs of protection exactly where you need it most - even when other probiotics fail.†
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How do I take Pure Saccharomyces Boulardii?
Take 1 capsule daily with or without food. Since it's acid-resistant, timing doesn't matter as much as with bacterial probiotics - it will survive.
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Can I take this while on antibiotics?
Yes! That's one of the key benefits. While antibiotics wipe out beneficial bacteria, S. Boulardii survives and can help maintain microbiome balance during and after antibiotic treatment.†
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Does this need to be refrigerated?
No, our S. Boulardii is shelf-stable and doesn't require refrigeration. This makes it perfect for travel or daily convenience while maintaining full potency.
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Is this tested and free from allergens?
Yes, it is independently tested and verified free from gluten, dairy, soy, and casein. It's also non-GMO and vegan.
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Do you offer a money-back guarantee?
60-day money-back guarantee, even if you've used the entire bottle. No questions asked. Applies to 1 bottle on your first order only.
Pure Saccharomyces Boulardii
Unflavored